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CASPASE 9
Descriptors Found:
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DeCS
Descriptor
English
:
Caspase 9
Descriptor
Spanish
:
caspasa 9
Descriptor
Portuguese
:
Caspase 9
Synonyms
English
:
Apoptotic Protease Activating Factor 3
Caspase-9
ICE LAP6 Protein
ICE Like Apoptotic Protease 6
ICE-LAP6 Protein
ICE-Like Apoptotic Protease 6
Pro Caspase 9
Pro-Caspase-9
Procaspase 9
Procaspase-9
Tree Number:
D08.811.277.656.262.500.126.550.900
D08.811.277.656.300.200.126.550.900
D12.644.360.024.131.155
D12.644.360.075.358.155
D12.644.360.075.405.550.900
D12.776.157.057.006.155
D12.776.476.024.139.155
D12.776.476.075.358.155
D12.776.476.075.405.550.900
Definition
English
:
A long pro-domain caspase that contains a CASPASE RECRUITMENT DOMAIN in its pro-domain region.
Caspase 9
is activated during cell stress by mitochondria-derived proapoptotic factors and by
CARD SIGNALING ADAPTOR PROTEINS
such as
APOPTOTIC PROTEASE-ACTIVATING FACTOR 1
. It activates
APOPTOSIS
by cleaving and activating
EFFECTOR CASPASES.
Entry Combination - descr/qualif
English
:
Caspase 9
/
antagonists & inhibitors
use
Caspase Inhibitors
History Note
English
:
2007(2005)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52228
Unique Identifier:
D053453
Occurrence in VHL
:
Similar:
DeCS